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In addition, the presence of leukocytes plays a role in inhibiting bacterial growth by improving soft-tissue healing, which would have been hindered by infection.[13] Magalon in 2016 proposed a DEAP classification which is based on dose, efficiency, purity and activation of platelets.[6] Further studies have been carried out to characterize and classify PRP based on preparation (centrifugation and use of anticoagulant), content (platelets, leukocytes and growth factors) and clinical applications