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Industry observers have noted that these drugs may prove "perpetually novel" through successive re-patenting for different uses, potentially maintaining monopoly positions even as earlier claims expire [40]

Zeng X, Xie YJ, Liu YT, Long SL, Mo ZC

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They are different molecules with different mechanisms, different efficacy profiles, and different regulatory statuses

Furthermore, ROCK inhibitors may exert protective effects on the germ cells within the testes, potentially reversing the negative impact of varicocele-induced oxidative stress