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Nonetheless, the exact mechanisms underlying the GLP-1 RA-associated HR acceleration are still unclear and these preliminary study results involving healthy male subjects cannot be over-generalized to a diabetic population using GLP-1 RAs

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Therefore, for subsequent analyses to provide actionable clinical probabilities, it is essential to select endpoints with consistent definitions and stable network connectivity (e.g., weight) and discuss their effect sizes and uncertainties within a standardized time window

Significant water absorption goes paracellular in kidney proximal tubules

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