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Radiotherapy increases tumor cell ferroptosis susceptibility, significantly inducing the expression of long-chain acyl-CoA synthetase 4 (ACSL4) and the ferroptosis inhibitors SLC7A11 and GPX4, thereby effectively suppressing tumor growth (109)

Ferroptosis-based therapies offer significant advantages, including personalized treatment tailored to genetic profiles, potential to overcome drug resistance, and synergy with other therapeutic modalities [161]

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The Effect of Long-Term Inorganic Iodine on Intrathyroidal Iodothyronine Content and Gene Expression in Mice with Graves' Hyperthyroidism

Thus, 22q11.2 deletion, which is related to ASD, is associated with both mitochondrial and synaptic abnormalities