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Another important fact is that this L-DOPA is co-administered with carbidopa, another important dopamine-replacement therapy for PD, aiming to increase the bioavailability of the substance and prevent early conversion into dopamine prior to entering the brain (Gandhi and Saadabadi, 2025)

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The first step of the pathway is the reduction of H 2 O 2 to water by the action of APX, using ascorbate acting as the electron donor