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This differs from the majority of heparin-binding proteins, which bind through basic amino acid sequences containing primarily lysine and arginine (Hileman et al., 1998), but is common for histidine-proline-rich glycoprotein (HPRG) (Burch et al., 1987)

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Informed consent was obtained from all individual participants included in the study

Vitamin D3 (Vit-D) is a lipid-soluble seco-steroid that exists in two forms as D 2 (ergocalciferol) derived mainly from plant sources and D 3 (cholecalciferol), which is present in higher animals 686

Keywords: aging in vitro , oocyte, antioxidant, Epitalon, mitochondria INTRODUCTION Healthy oocytes are essential for successful fertilization and subsequent embryo development [1]