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Accumulation of ATMs during obesity, particularly of pro-inflammatory ATMs, contributes to inflammation and insulin resistance of adipose tissue and was also found to be regulated by NF-B [119]

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Single-gene GSEA of feature genes Using the KEGG gene sets as a reference, we performed GSEA to identify the KEGG signaling pathways associated with the five feature genes, applying a threshold of adjusted P 1

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Recent studies have shown that the antioxidant and detoxification activities of Nrf2 confer chemo- and radio-resistance to cancer cells