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If hair thinning occurs during treatment, the cause is usually telogen effluvium, a temporary shedding phase triggered by major stressors such as rapid weight loss, illness, or surgery

doi: 10.1179/2046904712Z.00000000052

Risk of Hypokalemia (Low Potassium) Treatment with methylcobalamin can result in a boost in blood cell production in people with severe B12 deficiency and may potentially trigger hypokalemia

Higher plants do not concentrate methylcobalamin from the soil, making them a poor source of the substance as compared with animal tissues

All of the above are independent risk factors for cardiovascular disease