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This hasnt been confirmed in humans, but dont use semaglutide if you have a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2
A comparison of semaglutide and tirzepatide Feature Semaglutide Tirzepatide FDA Approval Year 2017 (injection), 2020 (oral) 2022 Average Weight Loss ~1015% of body weight ~1520% of body weight Dosage Forms Weekly injection, oral tablet Weekly injection only Common Side Effects Nausea, vomiting, diarrhea, constipation Nausea, vomiting, diarrhea, constipation Frequency Weekly (injection), daily (oral) Weekly injection Cost (approximate) $900$1,200/month $1,000$1,300/month (Keep in mind that numbers are averages
"Its also important to remember that starting a GLP-1 medication is not a substitute for taking care of overall health
(1) Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, Mu N, Gu J, Zhang W, Wang Y, Zhang Y, Zhang W