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We determined that the antioxidant transcriptional factor, NRF2 was constitutively activated in erastin-resistant cells and NRF2 transcriptionally upregulated CBS
Dehydration becomes dangerous when fluid loss exceeds 5% of body weightsigns include dark urine, dizziness when standing, and skin that stays "tented" when pinched for more than 2 seconds
These results suggested that keloid fibroblasts underwent pro-senescence regulation earlier compared with normal skin fibroblasts via p53-pS15 under serum limitation stimulus, and p53-pS15 and FOXO4 translocated from the nucleus to the cytoplasm during FOXO4-DRI treatment
5,6 Mosaicplasty, typically osteochondral autologous transplantation (OATs), is an open procedure where osteochondral plugs are harvested from non-weight bearing areas and transferred into the defect
K.ArfusoF.SamyR
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