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Compared with targeted drugs, traditional Chinese medicine has the characteristics of multiple targets and can regulate a variety of signal pathways, such as regulating ADAMTS18, ROS, Nrf2, GPX4 and other molecules, so as to regulate ferroptosis

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Similarly, it was recently reported that the expression of mitochondria-specific markers ( PGC1 , AMPK , SIRT1 , and cytochrome b , etc.) along with the protein levels of electron transport chain (complexes I, II, III, IV, and V) in osteocytes are not significant differences between bGH Tg and control mice (Liu et al., 2019)