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FDA has published a technical specifications document entitled "Submitting Clinical Trial Datasets to Evaluate the Impact of Immunogenicity on the Pharmacokinetics of a Drug," intended to help support the regulatory evaluation of immunogenicity data

Studies have shown that juniper berry extract can activate the ER stress pathway of human SH-SY5Y neuroblastoma cells, affect the expression of HSPA5 gene, and promote the expression and nuclear transport of p53

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The most commonly studied peptides were kisspeptin, GnRH analogs, and thymosin alpha-1

Advances in the understanding of cobalamin assimilation and metabolism