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As a result, a conceptual framework has emerged that positions MASLD as a disorder driven not only by nutrient overload and metabolic impairment, but also by the destabilization of a tripartite axis involving the circadian system, gut microbiota, and liver physiology

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Serum glutamate levels correlate with Gleason score and glutamate blockade decreases proliferation, migration, and invasion and induces apoptosis in prostate cancer cells