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For instance, zinc finger DHHC-type palmitoyltransferase 5 (DHHC5) promotes receptor-interacting serine/threonine-protein kinase 1 (RIPK1) transactivation to induce apoptosis [30], while DHHC5 also maintains autophagy homeostasis by modifying Beclin 1 [31], a key autophagy regulatory protein