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Intestinal immune cell-derived overactivation of NOX and inducible nitric oxide synthase (iNOS) generates excessive ROS, which oxidatively damage tight junction proteins in epithelial cells, compromising intestinal barrier integrity
Plasma levels decline significantly with age from approximately 200 ng/ml at age 20 to roughly 80 ng/ml by age 60
The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells
Feng W, Han X, Hu H, Chang M, Ding L, Xiang H et al (2021) 2D vanadium carbide MXenzyme to alleviate ROS-mediated inflammatory and neurodegenerative diseases
