Proc Natl Acad Sci U S A 121(14):e2308374121
James SJ, Melnyk S, Jernigan S, Cleves MA, Halsted CH, Wong DH, Cutler P, Bock K, Boris M, Bradstreet JJ, Baker SM, Gaylor DW: Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded in the mitochondrial genome, first identified in research published in Cell Metabolism in 2015
Researchers study it in the context of nicotinamide N methyltransferase activity, methylation related pathways, and cellular metabolism
Our advanced production facility manufactures high-purity glutathione using modern fermentation and purification technologies