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The standard titration schedule starts at 2.5 mg weekly for four weeks, then increases to 5 mg weekly for at least four weeks, with potential escalation to 7.5 mg, 10 mg, 12.5 mg, and 15 mg based on tolerability and response

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Nguyen AT, Mandard S, Dray C et al (2013) Lipopolysaccharides-Mediated increase in glucose-stimulated insulin secretion : involvement of the GLP-1 pathway

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The injection technique does not change