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Compounded semaglutide is prepared by a 503A pharmacy for individual prescriptions and is not an FDA-approved product, unlike the branded version

Optimal Bioavailability: It has the most active and readily absorbable form, hence enhances the bioavailability

According to Bernstein, the most common ongoing side effects were nausea, constipation and energy loss (all with 28% of patients reporting experiencing these side effects on an ongoing basis) as well as mood swings (27%), sagging loose skin (25%) and headaches (24%)

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Details regarding the literature search are provided in Supplementary Material 1 : Literature search