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TLDR: GLP-1s are a massive, fast-growing drug class for type 2 diabetes and weight loss

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Diabetes Obes Metab 25(1):5667 Rosenstock J, Wysham C, Frias JP et al (2021) Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial

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These occur most frequently during the initial titration phase, as dosage is increased from a starting level toward a therapeutic target

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Is it safe to microdose GLP-1 with methotrexate or biologics

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