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Additionally, irregular meals may exacerbate neurogenic inflammation and promote the release of pro-inflammatory mediators, including nitric oxide (NO), calcitonin gene-related peptide (CGRP), and other vasoactive substances implicated in migraine attacks

Dietary habits, exercise patterns, and dose escalation speed all shape individual experiences

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Trials of incretin-based therapies routinely monitor gastrointestinal symptoms such as nausea, vomiting, diarrhea, constipation, decreased appetite, and abdominal discomfort