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GLP-1R expression has also been demonstrated in the central nervous system 45 (CNS), but it is unlikely that such a large molecule as MEDI4166 can efficiently cross the blood brain barrier

Incretin mimetics, such as exenatide, are functional analogs of glucagon-like peptide-1 (GLP-1), a naturally occurring peptide that has the potential to significantly improve glycemic control in patients with diabetes

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It can lead to serious health complications if not managed properly, making effective treatment options crucial for maintaining blood sugar control and improving quality of life

Biomolecules 12:12