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Diabetes (2007) 56:294657

In a separate six-year trial of 320 participants with Type 2 diabetes treated with pioglitazone, metformin a diabetes drug used for blood glucose control and exenatide, about 75% of participants achieved an A1c of less than 6.5, while 70% of the subjects receiving standard therapy of metformin, sulfonylurea and insulin failed to achieve an A1c of less than 6.5 after 6 years

If your genetic profile shows strong GIP pathway activity but weak isolated GLP-1 response, tirzepatide's dual-agonist mechanism aligns better with your biology

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