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Yes, there can be side effects, although they are typically mild for most people

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HSS Journal

BPC 157 completely eliminated portal and caval hypertension, and markedly attenuated intracranial (superior sagittal sinus) hypertension and aortal hypotension (Figure 1)

A 42-year-old man dealing with fatigue and weight gain receives a different treatment plan than a 50-year-old athlete focused on recovery and performance, which is why men see meaningful results within 8 to 12 weeks rather than chasing generic protocols that never quite work