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Mechanistically stabilization of the SnCE1 non-acetylated monomer might contribute to this effect of SnCE1 acetylation, as exemplified by the observation that monomeric, non-acetylated SnCE1 Y212A shows stronger processing compared to tetrameric, non-acetylated SnCE1 C256A and monomeric, acetylated wild type SnCE1 (Fig