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This means it has not been studied in large-scale clinical trials to establish its safety and efficacy in this manner

Does berberine reduce the effectiveness of GLP-1 medications

The immunoreactive protein bands were detected with electrochemiluminescence (ECL) reagent (Millipore, Cat:# WBKLS0100) and acquired by ChemiDoc TM Touch Imaging System (BIORAD, Hercules, CA, USA)