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Assessment of a model-informed precision dosing platform use in routine clinical care for personalized busulfan therapy in the pediatric hematopoietic cell transplantation (HCT) population
Most patients notice improvements within weeks, and with the right support, the results can be life-changing
Immunofluorescence staining and counting To stained c-fos, TNC tissues were collected 2 h after the last NTG injection, while for staining other targets, TNC was collected 24 h after the last NTG administration
The third model patient-derived peripheral blood mononuclear cells (PBMCs) isolated from people actively diagnosed with TBM added another layer: cells already shaped by real disease, re-exposed to tuberculosis antigens in the laboratory