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Tirzepatide is a dual GIP/GLP-1 receptor agonist

But the results echo other research, including a study published in February in the Journal of Clinical Endocrinology & Metabolism that linked GLP-1 drugs to a higher risk of osteoporosis-related fractures in older adults with Type 2 diabetes

These conditions include type 2 diabetes, high blood pressure, or high cholesterol

Baseline characteristics, from Lambourg et al , Am J Kidney Dis, 2025 Table 2 shows that before weighting, patients who continued metformin differed from those who stopped it

Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain