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At the 12 mg dose level, here is what clinical trials reported: Nausea: 43.2% of participants (versus 10.7% on placebo) Diarrhea: 33.1% of participants (versus 13.4% on placebo) Constipation: 25.0% of participants (versus 8.7% on placebo) Vomiting: 20.9% of participants These percentages tell an important story
Glucose is a substrate for lipogenesis, and either dietary intake of glucose and fructose or hyperglycemia due to T2DM-associated insulin resistance can lead to hepatic de novo lipogenesis
Wegovy is available at a higher dosage than Ozempic, and in clinical trials, it has been more common for people to report side effects while using it
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