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While the potential of Dihexa in improving on certain cognitive functions and models like learning and long term memory capacity is promising, it is important to note that further research is necessary to validate its efficacy and safety as cognitive enhancer in human subjects
Methods Simplified human intestinal microbiota SIHUMIx The extended simplified human gut microbiota (SIHUMIx) comprises of eight species including Anaerostipes caccae (DSMZ 14662), Bacteroides thetaiotaomicron (DSMZ 2079), Bifidobacterium longum (NCC 2705), Blautia producta (DSMZ 2950), Clostridium butyricum (DSMZ 10702), Clostridium ramosum (DSMZ 1402), Escherichia coli K-12 (MG1655) and Lactobacillus plantarum (DSMZ 20174) ( in vitro culture ( Experimental set-up Continuous flow cultivation of SIHUMIx was carried out in an in vitro bioreactor system (Multifors 2 chemostat, Infors, Switzerland)
Adv Exp Med Biol 272:183-195
Neurosci Lett 569:7479 Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
Sterile water lacks preservatives, meaning each needle puncture increases contamination risk
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