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When it came time for the appointments, they took very good care of my son to make sure he was comfortable and also knew everything that he was going to experience

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Case 1 A 46-year-old female with history of rheumatoid arthritis and overweight (BMI of 35) currently on methotrexate (for total of 3 years) and semaglutide for weight loss (0.5 mg/subcutaneous weekly injection for total of 12 weeks) presented to the oral medicine clinic

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Moreover, SCFAs and tryptophan metabolites, as key mediators of bidirectional gut-brain communication, play essential roles in maintaining intestinal barrier integrity, modulating immune function, and transmitting signals via the vagus nerve (Dalile et al., 2019