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Wegovy Study 5 used exactly this structure: of 902 patients who entered a 20-week run-in that included 16 weeks of dose escalation, 803 reached the 2.4 mg maintenance dosage and were then randomised in a 2:1 ratio to continue or to receive placebo

This stabilization of blood sugar levels helps maintain energy throughout the day and reduces the likelihood of unhealthy cravings

This article reviews current evidence on how GLP-1 receptor agonists may influence chronic pain and explores what clinicians should consider when evaluating patient-reported improvements

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