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GHK-Cu is generally well-tolerated when dosed appropriately, but can carry risks if misused or combined with excess copper intake

However, it supports the cellular health and liver function that allow testosterone therapy to work optimally

These equivocal results comport with our understanding of sex differences, as observed in Figure 7 and Figure 8, which suggest that sex differences may reveal themselves differentially based on a subjects prior accumulation of tissue-level oxidative stress (which may be roughly assessed by time of day)

This decline correlates with reduced tissue regeneration capacity.[2][3] Structurally, GHK-Cu features a Cu(II) ion coordinated in a distorted square-planar pyramid by four nitrogen atoms: the amino-N of glycine, the amide-N of the Gly-His peptide bond, the imidazole-N of histidine, and an oxygen from water or a carboxyl group

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