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doi: 10.1016/j.plefa.2014.04.004

The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

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It binds the growth hormone receptor (GHR), a class I cytokine receptor present as a preformed homodimer on target cells throughout the body

In some cases, regular injections are recommended for lasting benefits, with results lasting about a month between sessions