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In regions such as the African and Asian continents and the Mediterranean river basin there exists a high frequency of the different variants of the enzymatic deficiency, whereas in China and Japan the frequency is low 23

Keremi, B., Lohinai, Z., Komora, P., Duhaj, S., Borsi, K., Jobbagy-Ovari, G., Kallo, K., Szekely, A

NAC has a longer general clinical history but a narrower longevity focus