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While niacin supplementation can improve muscle mass and positively impact lipid profiles 15 in mitochondrial disease patients and healthy population, it has been also associated with hyperglycemia 28

Reversible pulmonary hypertension, lactic acidosis, and rapidly evolving multiple organ failure as manifestations of shoshin beriberi

Peer reviewer acknowledgements BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance

The people eligible for the pilot program are in Part D prescription drug plans