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Efficacy and safety of mazdutide in Chinese patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 2 trial

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and elevate the expression of nuclear factor-erythroid 2-related factor 2 (Nrf2), a key transcription factor that governs the expression of a wide array of antioxidant and anti-inflammatory genes (65, 6769)

9 Materials and methods A structured literature review (PRISMA 2020) was conducted across PubMed, Embase, Cochrane Library, Scopus, and Google Scholar to 31 January 2026

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