in the other outcome, the injured tissue continues to deteriorate, and the mechanism of the persisting damage involves gliosis with the loss of support of neurotrophic factors, persistent inflammatory receptor activation, and changes in microglia and astrocytes that continue to release harmful cytokines, which promote neuronal death and axonal injury
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The defense also established that she had asked seven times to come to see him in the days before her death, and he reluctantly agreed only after she demanded it, and that she had threatened to kill Burke and to mutilate him