quitting glp 1 Many people start and stop GLP-1s. Here's why that may be a bad idea : NPR Meta Monday! WEIGHT REGAIN AFTER

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In this theory, reduced amounts of IGF-1 bioavailability would impact sebocyte proliferation via the loss of regulatory functions that IGF-1 has on 5-Reductase, while also causing impaired processing of secreted lipids in the interfollicular epidermis, which combined could result in the eventual keratinization of both the sebaceous gland and the impaired epithelial barrier of the follicular canal

doi: 10.1056/NEJM199807233390404

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