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Collectively, these human and experimental studies highlight a contribution of commensal microbiota to intestinal damage associated with CICB

In the future, individual aging maps can be constructed by integrating multidimensional data such as blood metabolomics, gut microbiota metagenomics and epigenetic clocks

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Quercetin and luteolin have been shown to inhibit the activity of cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, thereby reducing the production of pro-inflammatory prostaglandins and leukotrienes