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Both conditions increase the risk of cardiovascular disease and poor circulation, and those with both may have up to 5 times higher risk of lower extremity amputation and a higher probability of mortality at a younger age

IL-6 stimulates intestinal epithelial proliferation and repair after injury

Multiple signals in anterior cingulate cortex

It increases platelet count by binding and activating the human THPO receptor and is used to treat chronic idiopathic (immune) thrombocytopenic purpura (ITP)