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If weight regain begins despite lifestyle efforts, discuss with your provider whether transitioning to another weight management medication, such as semaglutide (Wegovy), liraglutide (Saxenda), naltrexone-bupropion (Contrave), or orlistat (Xenical) might be beneficial, considering your medical history and contraindications

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cpori in the gut microbiota of a group of participants may be the cause of their protection against heart metabolic diseases [227]

Better insulin sensitivity can positively affect androgen levels and menstrual regularity, though specific PCOS subgroup data from the trials is limited

Be Active Regular physical activity supports metabolism and long-term weight management