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Phase 2 trials show an average weight loss of 24% after 48 weeks on the highest dose of 12mg

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When to Talk to a Dermatologist If you've used Melanotan II or are considering it, or if you've noticed any new or changing spots on your skin, it's worth having a conversation with a board-certified dermatologist

FDA concluded in 2026 that evidence was insufficient to support wound-healing effectiveness