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In recent years, interest has arisen in the potential use of thymulin as a therapeutic agent

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Nahar et al

Using this definition, subnormal serum aminotransferase levels can occur due a deficiency of vitamin B 6 commonly seen in alcoholic liver disease as well as in celiac disease, Crohns disease, and CKD

Knowledge Gaps and Scholarly Debates USP37 as an Alternative Target: Recent discovery of the CHK2-USP37-FOXO4 stability axis suggests that small-molecule inhibitors of USP37 (e.g., Dacarbazine) may offer a more pharmacologically drug-like route to achieving the same senolytic effect as the FOXO4-DRI peptide (PNAS, 2026)