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That usually means documenting the reconstitution solvent used, keeping records at the lot level, minimizing repeated handling, and storing material under conditions consistent with the vendors instructions and the labs SOPs

Individuals who are severely immunocompromised, including those with HIV/AIDS with low CD4 counts, patients receiving chemotherapy, or those taking high-dose immunosuppressive medications, should consult their specialist before using probiotics due to rare reports of systemic infections caused by probiotic organisms

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Current Medical Research and Opinion, 23(10), 2597-2605