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GLP1-R is a class B G protein-coupled receptor, 25 and its expression has been reported in the cerebral cortex, especially the occipital and frontal lobes, hypothalamus, and thalamus, whereas lower levels are found in the caudate putamen, globus pallidus, and hippocampus

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When there is a change in hormone levels, such as during menopause or with certain medications, the bodys ability to control its temperature can be affected

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