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In contrast to the G-site that binds GSH across GST classes, the H-sites that bind various substrates have distinct variations in amino acid sequence and structural conformation [90]

These molecules are designed to be membrane-permeable, meaning they can cross cell membranes and access their target enzyme inside cells

Mishra, N

In the nervous system, inhibition of mTOR-mediated p70S6K and 4E-BP1 signalling usually promotes neuronal apoptosis 11