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Here's what to expect: Typical Semaglutide Titration: Weeks 1-4: 0.25 mg weekly (lowest dose) Weeks 5-8: 0.5 mg weekly Weeks 9-12: 1.0 mg weekly Weeks 13-16: 1.7 mg weekly Week 17+: 2.4 mg weekly (maintenance) Typical Tirzepatide Titration: Weeks 1-4: 2.5 mg weekly Weeks 5-8: 5 mg weekly Weeks 9-12: 7.5 mg weekly Weeks 13-16: 10 mg weekly Weeks 17-20: 12.5 mg weekly Week 21+: 15 mg weekly (maintenance) You'll have a nurse check-in at each dose adjustment to monitor tolerability, appetite suppression, weight change, and side effects

Patients may report that food simply tastes less appealing or that they experience diminished pleasure from eating

doi: 10.23736/S2724-6507.20.03369-6 135 FilippatosTDDerdemezisCSGaziIFNakouESMikhailidisDPElisafMS

Rybelsus provides oral semaglutide for diabetes management

It's intended to complement, not replace, the healthy habits that form the foundation of long-term success