Targeting the glucagon receptor family for diabetes and obesity therapy
Semaglutide is approved for weight loss in the UK and is sold under the brand name Wegovy
ADA: American Diabetes Association CGM: continuous glucose monitoring CKD: chronic kidney disease CVD: cardiovascular disease DM: diabetes mellitus DSMES: diabetes self-management education and support GLP-1 RAs: glucagon-like peptide-1 receptor agonists HF: heart failure MASLD: metabolic dysfunction-associated steatotic liver disease SGLT2: sodium-glucose cotransporter 2 T2DM: type 2 diabetes mellitus DT: Conceptualization, Formal analysis, Investigation, Resources, Data curation, Writingoriginal draft, Visualization
Areas of ongoing development include expanding the provider network to serve additional geographic markets, evaluating new formulations and medications as pharmaceutical innovation advances, enhancing digital health tools integrating wearables and tracking technologies, developing additional patient support resources including nutritional and behavioral health services, and refining treatment protocols based on real-world outcome data from the patient population
We typically reassess at week 4 if there's no movement at all, we look at quality of the product, technique, dose, and whether another peptide or therapy is a better fit