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Without intrinsic factor, vitamin B12 absorption is significantly impaired, which is why vitamin B12 deficiency is more common in individuals with gastrointestinal disorders that affect intrinsic factor production or absorption

Conversely, overtraining without adequate recovery can lead to chronic fatigue and muscle soreness, a condition often referred to as overtraining syndrome

Common contraindications include personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, or severe gastroparesis

Wang X, et al

Injectable vials: Indicated for severe cases with a dosage of 1 vial per day until symptoms begin to improve