And, further, for patients with type 2 diabetes (T2DM) taking a GLP-1, the risks are reduced by about 60% and 50%, respectively
What to expect: Average weight loss: 1015% of body weight Clothing fits looser, energy levels rise Better sleep and mood stability Blood pressure and cholesterol may start improving Achieve tip: Pair your medication with resistance training or walking
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Joshua Silva, MD Nov 7, 2025 13 min read Updated: Apr 17 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD As GLP-1 and GLP-1/GIP medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) continue to transform medical weight management, one question comes up repeatedly: Do these medications cause muscle lossor even muscle wasting
Microdosing falls entirely outside MHRA and NICE guidance, and off-label use is not routinely NHS-funded